Trifluoromethylation of aromatic compounds
โ Scribed by Yoshiro Kobayashi; Itsumaro Kumadaki
- Publisher
- Elsevier Science
- Year
- 1969
- Tongue
- French
- Weight
- 94 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
โฆ Synopsis
IReceived in Japan 4 August 1969; received in UK for publication 4 September 1969) V./e wish to rewort on. a new method to in.troduce Cl?3 group into the desired Wosition of the aromatic rinq.
๐ SIMILAR VOLUMES
The cycloaddition reactions of hexafluorobut-2-yne and 2Htrans heptafluorobut-2-ene with a variety of dienes has been investigated [l].
Aromatic trifluoromethyl compounds (2) are prepared by treatment of aromatic orthothio esters (Ll with 1,3-dibromo-5,5\_dimethylhydantoin (DBH) or N-bromosuccinimide (NBS) followed by HF/pyridine complex. The starting materials (1) were readily obtained by literature methodology.