Treatment of systemic sclerosis with recombinant interferon-γ. A phase I/II clinical trial
✍ Scribed by Bruce Freundlich; Sergio A. Jimenez; Virginia D. Steen; Thomas A. Medsger Jr.; Michelle Szkolnicki; Howard S. Jaffe
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 839 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Sixty consecutive patients with chronic hepatitis C were included in a randomized controlled trial of recombinant human interferon-%, vs. no treatment. Treated patients received tapering doses of interferon thrice weekly for 1 yr. Twenty treated cases (66.7%) normalized serum aminotransferase levels
and then 18 million for the fifth and sixth injections. The humoral immune responses of the patients were assessed by enzyme-linked immunoadsorbent assay, radioimmunoassay, and radioimmunoprecipitation. ## RESULTS. Thirteen of the 20 patients completed the immunization protocol. Eight of these 13