Phase II trial of recombinant interferon alfa-2 in the treatment of primary systemic amyloidosis
โ Scribed by Dr. Morie A. Gertz; Robert A. Kyle
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 311 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0361-8609
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A Phase I1 clinical trial of the combination of 5-fluorouracil (5-FU) and recombinant alpha-2a-interferon (a-2a-IFN) was conducted in 44 patients. Patients had not received chemotherapy previously and had measurable metastatic gastric carcinoma. 5-FU was administered as a continuous infusion at a do
## Background: Recombinant interferon-alpha (ifn) augments the cytotoxicity of both 5-fluorouracil (5-fu) and cisplatin in vitro. a phase ii study of 5-fu and ifn resulted in response rates of 25-27% in patients with metastatic esophageal carcinoma. ## Methods: A phase ii trial was initiated to d