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Treatment of refractory fludarabine induced autoimmune haemolytic with the anti-cd20 monoclonal antibody rituximab

โœ Scribed by R. SWORDS; A. NOLAN; M. FAY; J. QUINN; R. O'DONNELL; P. T. MURPHY


Book ID
108701737
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
77 KB
Volume
28
Category
Article
ISSN
1751-5521

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Rituximab is a chimeric anti CD-20 monoclonal antibody containing human IgG1 kappa constant regions, with murine variable regions. The anti-lymphoma effects of Rituximab are probably due to complement and antibody-dependent cell-mediated cytotoxicity, and induction of apoptosis. Phase II trials have