Treatment of Parkinson's Disease with levodopa and amantadine used as single drugs and in combined therapy
β Scribed by Noel Callaghan; Mary Mcllroy; Mary O'Connor
- Book ID
- 112971315
- Publisher
- Springer-Verlag
- Year
- 1974
- Tongue
- English
- Weight
- 594 KB
- Volume
- 143
- Category
- Article
- ISSN
- 1863-4362
No coin nor oath required. For personal study only.
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## Abstract The loss of beneficial effect of levodopa due to progression of the disease and alteration of receptor sensitivity makes the treatment of the advanced stadium of Parkinson's disease (PD) very difficult. In the past βdrug holidaysβ was used in attempt to resensitize dopamine receptors in
## Abstract The use of early combination therapy with bromocriptine (Br) and levodopa (LD) in Parkinson's disease is controversial. It has been suggested that treatment with this regimen would prevent or delay the onset of motor fluctuations and dyskinesia. Thus, some have recommended it as a stand