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PIRIBEDIL (ET 495) IN THE TREATMENT OF PARKINSON'S DISEASE COMBINED WITH AMANTADINE OR LEVODOPA

✍ Scribed by Noel Callaghan; Edmond Fitzpatrick; John B. O'Mahony

Book ID
114780471
Publisher
John Wiley and Sons
Year
1975
Tongue
English
Weight
367 KB
Volume
52
Category
Article
ISSN
0001-6314

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## Abstract The loss of beneficial effect of levodopa due to progression of the disease and alteration of receptor sensitivity makes the treatment of the advanced stadium of Parkinson's disease (PD) very difficult. In the past β€œdrug holidays” was used in attempt to resensitize dopamine receptors in