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Treatment of Cocaine-Alcohol Dependence with Naltrexone and Relapse Prevention Therapy

✍ Scribed by Joy M. Schmitz; Angela L. Stotts; Shelly L. Sayre; Katherine A. DeLaune; John Grabowski


Book ID
119769796
Publisher
Informa plc
Year
2004
Tongue
English
Weight
112 KB
Volume
13
Category
Article
ISSN
1055-0496

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## Abstract ## Introduction Oxcarbazepine (OXC) reduces high‐voltage‐activated calcium currents, thus reducing glutamatergic transmission at corticostriatal synapses. This effect on NMDA glutamatergic transmission may play a role against the increased glutamatergic transmission determined by alcoh