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Naltrexone and relapse prevention treatment for cocaine-dependent patients

✍ Scribed by Joy M Schmitz; Angela L Stotts; Howard M Rhoades; John Grabowski


Book ID
117493416
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
271 KB
Volume
26
Category
Article
ISSN
0306-4603

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## Abstract ## Introduction Oxcarbazepine (OXC) reduces high‐voltage‐activated calcium currents, thus reducing glutamatergic transmission at corticostriatal synapses. This effect on NMDA glutamatergic transmission may play a role against the increased glutamatergic transmission determined by alcoh