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Using Topiramate or Naltrexone for the Treatment of Alcohol-Dependent Patients

✍ Scribed by Gerardo Flórez; Paz García-Portilla; Sandra Álvarez; Pilar A. Saiz; Luis Nogueiras; Julio Bobes


Book ID
109124057
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
130 KB
Volume
32
Category
Article
ISSN
0145-6008

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## Abstract ## Introduction Oxcarbazepine (OXC) reduces high‐voltage‐activated calcium currents, thus reducing glutamatergic transmission at corticostriatal synapses. This effect on NMDA glutamatergic transmission may play a role against the increased glutamatergic transmission determined by alcoh