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Treatment of advanced head and neck squamous cell carcinoma (HNSCC) with intratumoral cisplatin/epinephrine (CDDP/epi) injectable gel: Phase III multicenter studies

✍ Scribed by J.A. Werner; D.J. Castro; W. Kehrl; A. Pluzanska; O. Arndt


Book ID
117658232
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
348 KB
Volume
37
Category
Article
ISSN
0959-8049

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## Background: The anti-cancer gene, e1a, can be complexed to a lipid carrier, dc-cholesterol:dope, to form tgdcc-e1a, which can be injected directly into tumors. ## Methods: Twenty-four patients with recurrent, unresectable, head and neck cancer were treated with intratumoral injections of tgdcc