Translocation t(12;22)(q13;q13) is a nonrandom rearrangement in clear cell sarcoma
β Scribed by B.R. Reeves; C.D.M. Fletcher; B.A. Gusterson
- Book ID
- 119105542
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 589 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0165-4608
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Karyotypic analysis of a clear cell sarcoma revealed a translocation t(12;22) (q13β14;q12) as a primary chromosomal change. This case is the third clear cell sarcoma cytogenetically analyzed; the two previously reported cases had t( 12;22)(p 11;p 11), and a complex karyotype with trisom
## Abstract Cytogenetic analysis of a shortβterm culture from a clear cell sarcoma revealed a complex karyotype with the mainline of 49,XY,t(7;18)(p11.2;q21.3), + der(7)t(7;18)(p11.2;q21.3), + 8, + der(8;17)(q10;q10),t(12;22)(q13;q12.2β12.3),add(13)(p13). An apparently identical translocation t(12;
## Abstract Clearcell sarcoma is a rare soft tissue sarcoma that displays certain similarities to malignant melanoma. In this paper we describe the karyotypic findings and in vitro growth characteristics of a shorttermcultured clearcell sarcoma. The cultured tumor cells had preserved immunohistoche