## Abstract Cytogenetic analysis of a short‐term culture from a clear cell sarcoma revealed a complex karyotype with the mainline of 49,XY,t(7;18)(p11.2;q21.3), + der(7)t(7;18)(p11.2;q21.3), + 8, + der(8;17)(q10;q10),t(12;22)(q13;q12.2–12.3),add(13)(p13). An apparently identical translocation t(12;
Translocation (12;22)(q13;q12) is characteristic for clear cell sarcoma of tendons and aponeuroses
✍ Scribed by Krzysztof Mrózek; Constantine P. Karakousis; Carlos Perez-Mesa; Clara D. Bloomfield
- Book ID
- 119106067
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 98 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0165-4608
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## Abstract Clearcell sarcoma is a rare soft tissue sarcoma that displays certain similarities to malignant melanoma. In this paper we describe the karyotypic findings and in vitro growth characteristics of a shorttermcultured clearcell sarcoma. The cultured tumor cells had preserved immunohistoche
The transcription factor gene CHOP was recently shown to be rearranged in myxoid liposarcoma with t( 12; I6)(q I );p I I). We have analyzed whether the CHOP gene is the target of rearrangements in pleomorphic adenoma and clear-cell sarcoma of tendons and aponeuroses with chromosome abnormalities of