t(12;22)(q13;q13) and trisomy 8 are nonrandom aberrations in clear-cell sarcoma
β Scribed by Eduardo Rodriguez; Chandrika Sreekantaiah; Victor E. Reuter; Robert J. Motzer; R.S.K. Chaganti
- Book ID
- 119105544
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 582 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0165-4608
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## Abstract Karyotypic analysis of a clear cell sarcoma revealed a translocation t(12;22) (q13β14;q12) as a primary chromosomal change. This case is the third clear cell sarcoma cytogenetically analyzed; the two previously reported cases had t( 12;22)(p 11;p 11), and a complex karyotype with trisom
## Abstract Cytogenetic analysis of a shortβterm culture from a clear cell sarcoma revealed a complex karyotype with the mainline of 49,XY,t(7;18)(p11.2;q21.3), + der(7)t(7;18)(p11.2;q21.3), + 8, + der(8;17)(q10;q10),t(12;22)(q13;q12.2β12.3),add(13)(p13). An apparently identical translocation t(12;