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Translocation (6;17)(q23;q11.2): a novel cytogenetic abnormality in congenital acute myeloid leukemia?

✍ Scribed by Elspeth C. Ferguson; Polly Talley; Ajay Vora

Book ID
113512709
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
80 KB
Volume
163
Category
Article
ISSN
0165-4608

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A new case of translocation t(6;11)(q21;q23) in a patient with therapy-related acute myeloblastic leukemia is reported. The translocation results in fusion of the MLL and AF6q21 genes. The breakpoint with AF6q21 is located within the sequences encoding the AF6q21 fork head motif. The similar locatio