Translational regulation of ornithine decarboxylase by polyamines
β Scribed by Lo Persson; Ingvar Holm; Olle Heby
- Book ID
- 115918391
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 412 KB
- Volume
- 205
- Category
- Article
- ISSN
- 0014-5793
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The management of polyamine synthesis and polyamine pools differs fundamentally from that of most other small molecular-weight endproducts. The polyamines are vital to growth and important cellular functions, but they are toxic in excess. I argue here that their multivaient cationic character, leadi
## Abstract Exogenous diamines and polyamines added to rat hepatoma (HTC) cells in culture rapidly decrease ornithine decarboxylase (ODC) activity. Previous evidence has suggested that these amines act either at the level of blocking new enzyme synthesis or by the induction of a nonβcompetitive pro