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Ornithine decarboxylase regulates the activity and localization of rhoA via polyamination

✍ Scribed by Laura T. Mäkitie; Kristiina Kanerva; Leif C. Andersson

Book ID
113955861
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
699 KB
Volume
315
Category
Article
ISSN
0014-4827

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In the present study we have examined the regulation of the polyamine biosynthetic pathway in a cell line deficient in ornithine decarboxylase (ODC) activity. These cells were unable to grow unless polyamines were provided in their growth medium. Seeding the cells in the absence of polyamines rapidl