๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Transgenes in autoimmunity

โœ Scribed by Myung-Shik Lee; Nora Sarvetnick


Book ID
103972872
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
739 KB
Volume
4
Category
Article
ISSN
0952-7915

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โœฆ Synopsis


The ability of transgenic mice to express a specific protein in a specific tissue has enabled the mechanisms of self-tolerance and autoimmunity to be elucidated. Further studies, combined with more sophisticated methods of gene targeting, will provide insights into the pathway leading from loss of self-tolerance to autoimmunity.


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Transgenic/knockout mice โ€” tools to stud
โœ Regula Mueller; Nora Sarvetnick ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 556 KB

Transgenic and knockout mice have been valuable tools for clarifying the roles of individual cell types and effector molecules in the pathogenesis of autoimmunity. During the past year, new strains have been added to the large array of transgenic mice, with broad or tissue-specific expression of tra