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Transgenes and knock-outs in autoimmunity

โœ Scribed by Christophe Benoist; Diane Mathis


Book ID
103972993
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
402 KB
Volume
5
Category
Article
ISSN
0952-7915

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Transgenes in autoimmunity
โœ Myung-Shik Lee; Nora Sarvetnick ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 739 KB

The ability of transgenic mice to express a specific protein in a specific tissue has enabled the mechanisms of self-tolerance and autoimmunity to be elucidated. Further studies, combined with more sophisticated methods of gene targeting, will provide insights into the pathway leading from loss of s