A panel of 6 human glioma cell lines was examined for TGF-1 responsiveness. U-178 MG and U-251 MG AgCl1 were significantly inhibited by TGF-1, while U-343 MGa 31L and U-343 MGa 35L were potently stimulated to proliferate. TGF-1 induced endogenous PAI-1 protein synthesis, Smad binding element/(CAG
✦ LIBER ✦
Transforming growth factor β (TGF β) and activin stimulate nuclear translocation of Smad proteins in granulosa cells.
✍ Scribed by E.A. McGee; J.I. Oakley; J. Xu
- Book ID
- 119417440
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 26 KB
- Volume
- 76
- Category
- Article
- ISSN
- 1556-5653
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Transforming growth factor-beta (TGF-P) is a polypeptide with multiple physiological functions. lsoforms of this growth factor have important roles in control of the cell cycle, in regulation of cell-cell interactions and in growth and development. Malignant transformation has been shown to be assoc