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Transforming growth factor (TGF)-β1 modifies Alzheimer's-type pathology in a transgenic mice and humans

✍ Scribed by Tony Wyss-Coray; Lisa Barcellos; Jorge Oksenberg; Ari Green; Eliezer Masliah; Lennart Mucke

Book ID: 117411514
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 173 KB
Volume: 21
Category: Article
ISSN: 0197-4580
DOI: 10.1016/s0197-4580(00)82362-3

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## Abstract The effects of EGF and TGF‐β1 on the proliferation of 2 ovarian carcinoma cell lines (IGROV1 and OVCCR1) were evaluated. The cell lines were adapted to grow in a restricted serum (0.5%) medium. EGF was required for proliferation of both ovarian cell lines. Low doses of TGF‐β1 inhibited