Transforming growth factor-beta (TGF-P) is a polypeptide with multiple physiological functions. lsoforms of this growth factor have important roles in control of the cell cycle, in regulation of cell-cell interactions and in growth and development. Malignant transformation has been shown to be assoc
Autocrine growth mechanism by transforming growth factor (TGF)-β1 and TGF-β1-receptor regulation by epidermal growth factor in a human endometrial cancer cell line IK-90
✍ Scribed by Masahiro Sakata; Hirohisa Kurachi; Hiromasa Ikegami; Hiroaki Jikihara; Ken-Ichiro Morishige; Akira Miyake; Naoki Terakawa; Osamu Tanizawa
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- French
- Weight
- 769 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
✦ Synopsis
Publication of the International Union Against Cancer Publication de I'Union lnternationale Contre le Cancer
📜 SIMILAR VOLUMES
## Abstract The effects of EGF and TGF‐β1 on the proliferation of 2 ovarian carcinoma cell lines (IGROV1 and OVCCR1) were evaluated. The cell lines were adapted to grow in a restricted serum (0.5%) medium. EGF was required for proliferation of both ovarian cell lines. Low doses of TGF‐β1 inhibited
A panel of 6 human glioma cell lines was examined for TGF-1 responsiveness. U-178 MG and U-251 MG AgCl1 were significantly inhibited by TGF-1, while U-343 MGa 31L and U-343 MGa 35L were potently stimulated to proliferate. TGF-1 induced endogenous PAI-1 protein synthesis, Smad binding element/(CAG
## Abstract Follistatin‐related gene (FLRG) is a member of the follistatin family of proteins and interacts with transforming growth factor (TGF) superfamily proteins like follistatin. To understand the expression level of FLRG in brain tissue, we examined whether primary neurons and glial cells fr