Transformed SV3T3 cells have a reduced lysosomal compartment and lower levels of enzyme activity than 3T3 cells
β Scribed by V. Kundra; M.F. Dean
- Book ID
- 115892521
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 899 KB
- Volume
- 189
- Category
- Article
- ISSN
- 0014-4827
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## Abstract Cell strains isolated from an established line of SV40βtransformed mouse 3T3 cells (SV3T3) showed large variations in the various parameters of transformation, viz. saturation density, serum requirement, contact inhibition of movement and of growth and ConcanavalinβAβmediated agglutinab
## Abstract 3T3 mouse fibroblasts in 10% calf serum cease to increase in number at confluence. SV40βtransformed 3T3 cells lose their sensitivity to this growth control and so are able to reach multilayered cell densities. We previously described a polyploid revertant line F1SV101, isolated from a S