Transformations of β-d-xylofuranosyl nucleosides. The effective synthesis of 2′,3′-dideoxy-2′,3′-didehydrothymidine
✍ Scribed by A. G. Mustafin; M. V. Suyundukova; R. R. Gataullin; L. V. Spirikhin; I. B. Abdrakhmanov; G. A. Tolstikov
- Publisher
- Springer
- Year
- 1997
- Tongue
- English
- Weight
- 110 KB
- Volume
- 46
- Category
- Article
- ISSN
- 1573-9171
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5 0 -O-Benzoyl-2,3 0 -anhydrothymidine. 60% Methanol in water, retention time 13.1 min. \* 2 0 ,3 0 -Dideoxy-2 0 ,3 0 -didehydrothymidine. Solvents: A -water; B -methanol. Program: 0-40% B/A in 40 min, retention time 33.9 min. TLC was carried out on Silufol plates (Czech Republic). \* 5 0 -O-Benzo
## Abstract The α,β‐unsaturated D‐sugar aldehyde 2, prepared from tri‐__O__‐acetyl‐D‐glucal, was converted into 1‐__O__‐acetyl‐3‐azido‐2,3‐dideoxy‐α‐D‐__arabino__‐pyranose (3) by reaction with sodium azide in a mixture of acetic acid and water followed by acetylation. Reaction of 3 with silylated p