Transformation of granulocytes to macrophages in bone marrow colonies in vitro
โ Scribed by Donald Metcalf
- Publisher
- John Wiley and Sons
- Year
- 1971
- Tongue
- English
- Weight
- 295 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0021-9541
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โฆ Synopsis
Abstract
Single cells from developing two day granulocytic bone marrow colonies were transfered in agar cultures. After three to five days, 48 of 239 transfered single cells had transformed to single macrophages or proliferated to form aggregates of pure macrophages or mixed macrophageโgranulocyte aggregates. Some granulocytes in colonies developing in vitro from bone marrow cells appear to have the capacity to transform to macrophages.
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