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Transformation of granulocytes to macrophages in bone marrow colonies in vitro

โœ Scribed by Donald Metcalf


Publisher
John Wiley and Sons
Year
1971
Tongue
English
Weight
295 KB
Volume
77
Category
Article
ISSN
0021-9541

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โœฆ Synopsis


Abstract

Single cells from developing two day granulocytic bone marrow colonies were transfered in agar cultures. After three to five days, 48 of 239 transfered single cells had transformed to single macrophages or proliferated to form aggregates of pure macrophages or mixed macrophageโ€granulocyte aggregates. Some granulocytes in colonies developing in vitro from bone marrow cells appear to have the capacity to transform to macrophages.


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