A gene-controlling response of bone marrow progenitor cells to granulocyte-macrophage colony stimulating factors
β Scribed by Gary S. Lazar; Diana H. Quon; Aldons J. Lusis
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 618 KB
- Volume
- 124
- Category
- Article
- ISSN
- 0021-9541
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β¦ Synopsis
Kosaka, K. (1977) Demonstration of granulopoietic factods) in the plasma of nude mice transplanted with a human lung cancer and in the tumor tissue. Blood, 49:845-852. Apte, R.N., and Pluznik, D.H. (1976) Genetic control of lipopolysaccharide induced generation of serum colony stimulating factor and proliferation of splenic granulocyte/macrophage precursor cells. J.
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Combinations of low dosages of purified recombinant human (rh) macrophagecolony stimulating factor (M-CSF; also termed CSF-1) and rh granulocyte-colony stimulating factor (G-CSF) were compared alone and in combination for their influence on the cycling rates and numbers of bone marrow and splenic gr
The metabolic function and GM-CSF production rates of adherent human bone marrow stromal cells were investigated as functions of medium and serum feeding rates. A range of medium exchange schedules was studied, ranging from a typical Dexter culture protocol of one weekly medium exchange to a full me