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Transcriptional regulation by the nuclear receptor superfamily

✍ Scribed by Victor C. Yu; Anders M. Näär; Michael G. Rosenfeld

Publisher: Elsevier Science
Year: 1992
Tongue: English
Weight: 646 KB
Volume: 3
Category: Article
ISSN: 0958-1669
DOI: 10.1016/0958-1669(92)90002-z

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✦ Synopsis

In the past year, additional experimental data have expanded our understanding of the molecular mechanisms that underlie nuclear receptor control of regulatory programs. It is increasingly clear that steroid members (e.g. glucocorticoid and estrogen) and non-steroid members (e.g. retinoic acid, thyroid hormone, and vitamin D) of the nuclear receptor superfamily may utilize distinct strategies in achieving their complex control of gene regulation.

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