Transcriptional analysis of the PTEN/MMAC1 pseudogene, ΨPTEN
✍ Scribed by Fujii, Gregory H; Morimoto, Alyssa M; Berson, Amy E; Bolen, Joseph B
- Book ID
- 110061940
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 241 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0950-9232
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Recently, a putative tumor suppressor gene, PTEN/MMAC1, has been identified at chromosome 10q23.3, which encodes a 403 amino acid dual-specificity phosphatase containing a region of homology to tensin and auxillin. Somatic mutations of the PTEN/MMAC1 gene have been identified in a number of cancer c
The PTEN/MMAC1/TEP1 gene has been isolated as a tumor suppressor gene that is altered in several types of human tumors including brain, breast, and prostate cancers. In the present study, we report PTEN/MMAC1/TEP1 alterations in human lung cancers. Intragenic homozygous deletions were detected in 6