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Transcription Factories and Spatial Organization of Eukaryotic Genomes

โœ Scribed by S. V. Razin; A. A. Gavrilov; O. V. Yarovaya


Book ID
110155465
Publisher
Springer
Year
2010
Tongue
English
Weight
291 KB
Volume
75
Category
Article
ISSN
0006-2979

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## The nuclear DNA of eukaryotes is organized into a series of loops each topologically anchored by elements of the nuclear matrix. Evidence is reviewed which indicates that the anchorage points of the loops are formed by transcriptionally active genes and that individual loops function as replicons