Studies related to the synthesis of mayt
β
Derek H.R. Barton; Michel BΓ©nΓ©chie; FranΓ§oise Khuong-Huu; Pierre Potier; Victor
π
Article
π
1982
π
Elsevier Science
π
French
β 196 KB
Two approaches to the partial synthesis of C1-Cs of a bis-nor maytansinoid 1 have been investigated starting on the one hand with (S)-(-)-malic acid and on the other, with D-(+)-ribonolactone. 2 Maytansinoids are interesting naturally occurringIantitumor agents . 3 Extensive work has already been ca