Traceless Solid-Phase Synthesis of 2,4-Diaminoquinazolines
โ Scribed by Wilson, Lawrence J.
- Book ID
- 126135642
- Publisher
- American Chemical Society
- Year
- 2001
- Tongue
- English
- Weight
- 80 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1523-7060
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๐ SIMILAR VOLUMES
An effective traceless solid-phase synthesis of chloro-diaminopyrimidines via an amino-de-chlorination reaction of polymerbound 4-alkoxycarbonylamino-2,6-dichloropyrimidines has been developed. After release from the polymer the target molecules were obtained in good to excellent purity, although wi
A traceless solid-phase synthesis of 2-imidazolones has been developed. Polymer-bound glycerol resin was reacted with bromoacetaldehyde diethyl acetal to give the cyclic acetal bromide on the solid support. Amination of the resin-bound acetal bromide followed by urea formation by reaction with isocy