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Toxoplasma gondiiinfection inhibits the mitochondrial apoptosis through induction of Bcl-2 and HSP70

✍ Scribed by Il-Young Hwang; Juan Hua Quan; Myoung-Hee Ahn; Hassan Ahmed Hassan Ahmed; Guang-Ho Cha; Dae-Whan Shin; Young-Ha Lee


Book ID
106129991
Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
237 KB
Volume
107
Category
Article
ISSN
1432-1955

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## Abstract Bcl‐2 family members are the arbiters of mitochondrial apoptotic pathway, which is conserved through evolution. The stoichiometry of pro‐ versus antiapoptotic Bcl‐2 family members in the cell determines whether the cell lives or dies. This fine balance is regulated at the transcriptiona