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Induction of apoptosis by p110C requires mitochondrial translocation of the proapoptotic BCL-2 family member BAD

โœ Scribed by Chen Chen; Jun Yan; Qing Sun; Luyang Yao; Yongzhi Jian; Jieqiong Lu; Jianxin Gu

Book ID
116466336
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
441 KB
Volume
580
Category
Article
ISSN
0014-5793

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The anti-apoptotic members of the Bcl-2 family, such as Bcl-2 and Bcl-XL, play a central role in preventing the induction of apoptosis via the intrinsic apoptotic pathway. It has been previously shown that induction of apoptosis by the pro-apoptotic Bcl-2 family member Bok is not antagonized by eith