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JNK Suppresses Apoptosis via Phosphorylation of the Proapoptotic Bcl-2 Family Protein BAD

✍ Scribed by Chenfei Yu; Yuzuru Minemoto; Jiyan Zhang; Jing Liu; Fangming Tang; Truc N. Bui; Jialing Xiang; Anning Lin


Book ID
117737341
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
541 KB
Volume
13
Category
Article
ISSN
1097-2765

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## Abstract Bcl‐2 family members are the arbiters of mitochondrial apoptotic pathway, which is conserved through evolution. The stoichiometry of pro‐ versus antiapoptotic Bcl‐2 family members in the cell determines whether the cell lives or dies. This fine balance is regulated at the transcriptiona