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Toxicological evaluation of norpace® after intravenous administration to rat and dog

✍ Scribed by K.S. Rao; R. Stejskal; D.M. Ferguson; R.G. McConnell

Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
537 KB
Volume
7
Category
Article
ISSN
0300-483X

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The pharmacokinetic parameters including tissue distribution and/or biliary excretion of DA-1131, a new carbapenem, were evaluated after intravenous (iv) administration to mice, rats, rabbits, and dogs. After i.v. administration to mice (20, 50, 100, and 200 mg kg-1), rats (50, 100, 200, and 500 mg