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Toxicity of methoxyacetic acid in rats

โœ Scribed by MILLER, R; CARREON, R; YOUNG, J; MCKENNA, M

Book ID
122028322
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
302 KB
Volume
2
Category
Article
ISSN
0272-0590

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The ethylene glycol ether 2-methoxyethanol (ME) and its oxidation product methoxyacetic acid (MAA) are selective embryotoxins and equipotent as inducers of digit malformations when given by gavage to pregnant Cr1:CD-1 ICR BR mice on gestation day 11. Earlier observations showed that the teratogenic