Teratogenicity of dimethoxyethyl phthalate and its metabolites methoxyethanol and methoxyacetic acid in the rat
โ Scribed by Ritter, E. J. ;Scott, W. J. ;Randall, J. L. ;Ritter, J. M.
- Book ID
- 112217496
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 537 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0040-3709
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The rat foetus, in contrast with the maternal liver and placenta, has little or no ability t o hydrolyse di-(2-methoxyethy1)-phthalate (DMEP) to mono-2-methoxyethylphthalate (MMEP). At short times after the administration of DMEP to the dam on the 14th day of gestation, however, both the di-and mono
The ethylene glycol ether 2-methoxyethanol (ME) and its oxidation product methoxyacetic acid (MAA) are selective embryotoxins and equipotent as inducers of digit malformations when given by gavage to pregnant Cr1:CD-1 ICR BR mice on gestation day 11. Earlier observations showed that the teratogenic