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Towards the stereoselective synthesis of α-methylated (2S,3aS,7aS)-octahydroindole-2-carboxylic acid

✍ Scribed by Francisco J. Sayago; M. Isabel Calaza; Ana I. Jiménez; Carlos Cativiela


Book ID
108284412
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
496 KB
Volume
19
Category
Article
ISSN
0957-4166

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The synthesis of enantiomerically pure a-amino acid (2S,3aS,6R,7aS)-2-carboxy-6-chlorooctahydroindole (L-Ccoi) is described. NMR data of L-Ccoi 3 are very different from those reported for the azabicyclic core of aeruginosins 205, indicating that the structure of these aeruginosins needs to be revis