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Towards models for the structure and the function of the active site of galactose-oxidase

โœ Scribed by D. Zurita; J.L. Pierre


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
44 KB
Volume
59
Category
Article
ISSN
0162-0134

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A Structural Model for the Galactose Oxi
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Galactose oxidase (GO) contains one copper ion at its active site and performs a two-electron oxidation of primary alcohols to aldehydes, coupled with a reduction of O 2 to eomer in 68 % yield. The entire sequence was performed in 24 linear steps from (S)-malic acid. The material thus obtained was s