## Abstract The active site of the enzyme galactose oxidase (GOase) contains squareโpyramidal monocopper site, one of whose ligands is a tyrosinate sideโchain that is oxidized to an unusually stable radical in the active enzyme. The structure of this nonโinnocent tyrosinate is unique in two ways. F
โฆ LIBER โฆ
Modeling of the Chemistry of the Active Site of Galactose Oxidase
โ Scribed by Jason A. Halfen; Dr. Victor G. Young Jr; Prof. William B. Tolman
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 543 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
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Galactose oxidase (GO) contains one copper ion at its active site and performs a two-electron oxidation of primary alcohols to aldehydes, coupled with a reduction of O 2 to eomer in 68 % yield. The entire sequence was performed in 24 linear steps from (S)-malic acid. The material thus obtained was s
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