Toward the Total Synthesis of Spirastrel
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Alois Fürstner; Michaël D. B. Fenster; Bernhard Fasching; Cédrickx Godbout; Kari
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Article
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2006
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John Wiley and Sons
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English
⚖ 240 KB
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The novel antimitotic agent spirastrellolide A (1), isolated from the Caribbean sponge Spirastrella coccinea, is endowed with potent and selective phosphatase inhibitory properties. [1] Although the relative stereochemistry of each individual domain embedded into the macrocyclic frame of this marine