Toward a Total Synthesis of Pristinamycin II B ; a Chiron Approach to a C-9/C-16 Fragment. -Starting from readily available (S)-malic acid derivative (I), an appreciable amount (ca. 2 g) of the title fragment (XV) is prepared using the Grignard reaction of the propargyl diol (VI) as the key step. T
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Toward a total synthesis of pristinamycin IIB; a chiron approach to a C-9/C-16 fragment
β Scribed by P. Breuilles; D. Uguen
- Book ID
- 108386710
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 277 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
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Both homochiral acetates 4d and 5f, which were obtained by lipase-catalysed acetylation of either the tetraol 4a or the diol 5e, respectively, have been converted stereoconvergently into a C-5/C-9 fragment of the title antibiotic.
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