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Totally Selective Ring-Opening of Amino Epoxides with Ketones: A General Entry to Enantiopure (2R,3S)- and (2S,3S)-3-Aminoalkano-1,2-diols.

✍ Scribed by Jose M. Concellon; Jose Ramon Suarez; Santiago Garcia-Granda; M. Rosario Diaz


Publisher
John Wiley and Sons
Year
2005
Weight
34 KB
Volume
36
Category
Article
ISSN
0931-7597

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## Abstract An easy technique for introduction of tritium into the 1‐position of sphingosine was developed, employing regiospecific oxidation of the primary hydroxy group followed by reduction with NaB^3^H~4~. An improved preparation of __N__,__N__‐dimethylsphingosine and its quaternization are als