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Total synthesis of unsaturated trihydroxy C18 fatty acids

✍ Scribed by Benjamin Gossé-Kobo; Paul Mosset; René Grée

Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
145 KB
Volume
30
Category
Article
ISSN
0040-4039

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✦ Synopsis

The total synthesis, in chiral form, of unsaturated trlhydroxy Clg fatty acids 13 and 14 as methyl esters, s&ting from natural tartaric acid via the key intermediate aldehyde 5 is reported.

Little is known about the biological importance of oxygenated fatty acids metabolitcs in vegetals.

Then, it is interesting to point out that Kato and coworkers isolated from rice plants several oxygenated Cl8 fatty acids which can act as self-defense substances against rice blast disease (1). Among these were the triols 1 to 4.

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