Synthesis of lipoxins: Total synthesis of conjugated trihydroxy eicosatetraenoic acids
β Scribed by Julian Adams; Brian J. Fitzsimmons; Joshua Rokach
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- French
- Weight
- 208 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The total synthesis, in chiral form, of unsaturated trlhydroxy Clg fatty acids 13 and 14 as methyl esters, s&ting from natural tartaric acid via the key intermediate aldehyde 5 is reported. Little is known about the biological importance of oxygenated fatty acids metabolitcs in vegetals. Then, it
A total convergent synthesis of lipoxins A4 and B4 has been carried out via four optically pure a-hydroxy and a$-dihydroxyaldehydes, obtained from D-isoascorbic acid as a single starting material. Connection by a six carbons unit uses Wittig-type reactions notably involving a stabilized arsonium yl