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Total Synthesis of the Polyenoyltetramic Acid Polycephalin C.

โœ Scribed by Deborah A. Longbottom; Angus J. Morrison; Darren J. Dixon; Steven V. Ley


Book ID
101954400
Publisher
John Wiley and Sons
Year
2003
Weight
64 KB
Volume
34
Category
Article
ISSN
0931-7597

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Total synthesis of the polyenoyltetramic
โœ Deborah A Longbottom; Angus J Morrison; Darren J Dixon; Steven V Ley ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 325 KB

The total synthesis of the polyenoyltetramic acid polycephalin C is described. Key steps of the synthesis include a double Swern oxidation, double Takai reaction and a double Stille reaction. In addition, the absolute stereochemistry of the ring junction has been determined by synthesis of both isom