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Total synthesis of the polyenoyltetramic acid mycotoxin erythroskyrine †

✍ Scribed by Dixon, Darren J.; Ley, Steven V.; Gracza, Tibor; Szolcsanyi, Peter


Book ID
120763417
Publisher
Royal Society of Chemistry
Year
1999
Weight
169 KB
Volume
8
Category
Article
ISSN
1472-7781

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Total synthesis of the polyenoyltetramic
✍ Deborah A Longbottom; Angus J Morrison; Darren J Dixon; Steven V Ley 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 325 KB

The total synthesis of the polyenoyltetramic acid polycephalin C is described. Key steps of the synthesis include a double Swern oxidation, double Takai reaction and a double Stille reaction. In addition, the absolute stereochemistry of the ring junction has been determined by synthesis of both isom