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Total Synthesis of the CP-Molecules (CP-263,114 and CP-225,917, Phomoidrides B and A). 1. Racemic and Asymmetric Synthesis of Bicyclo[4.3.1] Key Building Blocks

✍ Scribed by Nicolaou, K. C.; Jung, J.; Yoon, W. H.; Fong, K. C.; Choi, H.-S.; He, Y.; Zhong, Y.-L.; Baran, P. S.


Book ID
121427639
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
153 KB
Volume
124
Category
Article
ISSN
0002-7863

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The Absolute Configuration and Asymmetri
✍ K.β€…C. Nicolaou; Jae-Kyu Jung; Wonβ€…Hyung Yoon; Yun He; Yong-Li Zhong; Philβ€…S. Bar πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 104 KB πŸ‘ 2 views

The stunning molecular structures [1] coupled with the promising biological activities of the CP compounds (pho-moidrides, [2] 1 a and b; Figure 1) have inspired numerous studies directed at their total synthesis. [3] In 1999 we reported the first total synthesis of these molecules in their racemic