𝔖 Bobbio Scriptorium
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Total Synthesis of the Antibiotic BE-43472B

✍ Scribed by Yamashita, Yu; Hirano, Yoichi; Takada, Akiomi; Takikawa, Hiroshi; Suzuki, Keisuke


Book ID
120464421
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
754 KB
Volume
52
Category
Article
ISSN
0044-8249

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📜 SIMILAR VOLUMES


Total Synthesis and Absolute Configurati
✍ K. C. Nicolaou; Yee Hwee Lim; Jochen Becker 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 449 KB

## Abstract **Einladung zum T**: Erstmals wurde der T‐förmige Bisanthrachinon‐Naturstoff BE‐43472B durch Totalsynthese hergestellt und seine Absolutkonfiguration aufgeklärt. Wesentliche Schritte der zentralen Kaskadensequenz sind eine Diels‐Alder‐Reaktion, die Bildung eines Halbketals und eine nucl

Total Synthesis and Absolute Configurati
✍ K. C. Nicolaou; Yee Hwee Lim; Jochen Becker 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 449 KB

## Abstract **An‐T‐biotic**: The first total synthesis of the T‐shaped bisanthraquinone natural product BE‐43472B was accomplished and its absolute configuration assigned. Key transformations in the pivotal cascade sequence include a Diels–Alder reaction, a hemiketal formation, and a nucleophilic a

Total synthesis of antibiotic karnamicin
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The novel antifungal karnamicin B, (1), 5-hydroxy-3,4-dimethoxy-2-(2-(4-oxopentyl)-4-thiazolyl}pyridine-6-carboxamide was first synthesized via the formation of partially methylated trihydroxy pyridine by ring-transformation from the corresponding furan derivative and subsequent regioselective intro