## Abstract **Einladung zum T**: Erstmals wurde der T‐förmige Bisanthrachinon‐Naturstoff BE‐43472B durch Totalsynthese hergestellt und seine Absolutkonfiguration aufgeklärt. Wesentliche Schritte der zentralen Kaskadensequenz sind eine Diels‐Alder‐Reaktion, die Bildung eines Halbketals und eine nucl
Total Synthesis of the Antibiotic BE-43472B
✍ Scribed by Yamashita, Yu; Hirano, Yoichi; Takada, Akiomi; Takikawa, Hiroshi; Suzuki, Keisuke
- Book ID
- 120464421
- Publisher
- John Wiley and Sons
- Year
- 2013
- Tongue
- English
- Weight
- 754 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0044-8249
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## Abstract **An‐T‐biotic**: The first total synthesis of the T‐shaped bisanthraquinone natural product BE‐43472B was accomplished and its absolute configuration assigned. Key transformations in the pivotal cascade sequence include a Diels–Alder reaction, a hemiketal formation, and a nucleophilic a
The novel antifungal karnamicin B, (1), 5-hydroxy-3,4-dimethoxy-2-(2-(4-oxopentyl)-4-thiazolyl}pyridine-6-carboxamide was first synthesized via the formation of partially methylated trihydroxy pyridine by ring-transformation from the corresponding furan derivative and subsequent regioselective intro