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Total Synthesis of the Ammosamides

✍ Scribed by Hughes, Chambers C.; Fenical, William


Book ID
120305176
Publisher
American Chemical Society
Year
2010
Tongue
English
Weight
158 KB
Volume
132
Category
Article
ISSN
0002-7863

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Efficient Total Synthesis of Ammosamide
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Short and straightforward total synthesi
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A simple and five steps total synthesis of Ammosamide B has been developed. The tricyclic pyrroloquinoline in Ammosamides was constructed in one step based on Doebner-Miller reaction between 1,3-diamine-4,6-dinitrobenzene 8 and dimethyl-2-oxo glutaconate 9.