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Efficient Total Synthesis of Ammosamide B

✍ Scribed by Reddy, P. V. Narasimha; Banerjee, Biplab; Cushman, Mark


Book ID
126236256
Publisher
American Chemical Society
Year
2010
Tongue
English
Weight
166 KB
Volume
12
Category
Article
ISSN
1523-7060

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A simple and five steps total synthesis of Ammosamide B has been developed. The tricyclic pyrroloquinoline in Ammosamides was constructed in one step based on Doebner-Miller reaction between 1,3-diamine-4,6-dinitrobenzene 8 and dimethyl-2-oxo glutaconate 9.

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